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C-2901 - Diagnostic accuracy of biparametric vs multiparametric MRI in prostate cancer local staging

F. Misischi, R. Faletti, F. Gentile, P. Cimpoesu, G. Calleris, L. Molinaro, J. Giglio, P. Gontero, P. Fonio; Turin/IT Type: Scientific Exhibit
Area of Interests: Pelvis, Genital / Reproductive system male, Oncology
Imaging Techniques: MR, MR-Diffusion/Perfusion
Procedures: Staging, Imaging sequences, Computer Applications-Detection, diagnosis
Special Focuses: Pathology, Cancer, Neoplasia
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Aims and objectives: MRI diagnostic performance in detection of prostate cancer is widely demonstrated although MR in local staging is still debated. Our aim was to compare the performance of biparametric (T2WI+DWI) and multiparametric MRI (T2WI+DWI+DCE) in prostate cancer local staging.

Methods and materials: Fifty-seven patients with pre-operative MR were retrospectively evaluated. Patients were enrolled by using the following inclusion criteria: (a) pre-operative multiparametric MRI (T2WI+DWI+DCE); (b) pre-operative MRI performed at least three weeks after prostate biopsy; (c) radical prostatectomy wit[...]

Results: The inter-observer agreement was good (κ=0,71±0,15). There were no statistically significant differences between biparametric and multiparametric MRI in the performance of MR in local staging.   Sensitivity of biparametric and multiparametric MRI for F-EPE was respectively 65,4% and 55,8% (p=[...]

Conclusion: In our study multiparametric prostate MRI did not increase the accuracy of capsular invasion and extracapsular tumor extension compared to biparametric analysis. Prostate cancer MR local staging accuracy is higher for extensive “non-focal” extracapsular tumor extension than for limited “focal” capsu[...]

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References: 1. Weinreb JC, Barentsz JO, Choyke PL, Cornud F, Haider MA, Macura KJ, Margolis D, Schnall MD, Shtern F, Tempany CM, Thoeny HC, Verma S. PI-RADS Prostate Imaging - Reporting and Data System: 2015, Version 2. Eur Urol. 2016 Jan;69(1):16-40. doi: 10.1016/j.eururo.2015.08.052. Epub 2015 Oct 1. PMI[...]

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