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B-1383 - Role of tomosynthesis-guided biopsy (3D VAB) in reducing uncertain biological potential lesions (B3) overtreatment, detected with tomosynthesis as architectural distortions

G. Romanucci1, S. Brunelli1, P. Bricolo1, L. Cugola1, A. Caneva2, F. Caumo1; 1 Verona/IT 2 San Bonifacio/IT Type: Scientific Paper
Area of Interest: Breast
Imaging Technique: Mammography
Procedure: Biopsy
Special Focus: Cancer
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Purpose: Aim of this study is to assess the diagnostic accuracy of digital breast tomosynthesis-guided vacuum assisted breast biopsy (DBT-VAB) to characterize DBT-detected architectural distortions and to reduce overtreatment of B3 lesions.

Methods and materials: Study setup and patients 123 DBT-VAB were performed from April 2015 to April 2016, 50 of them on architectural distortions.   Biopsy Technique DBT-VAB was performed by using a platform which allows to acquire a three-dimensional tomosynthesis (Selenia Dimensions 3D; Hologic) and a C-View softw[...]

Results: 123 lesions underwent to DBT-VAB, with successful sampling of the lesions in all the cases (100%). The target lesion appearance at DBT was described in Fig.1.  Of the 50 architectural distortions (mean lesions size 14.42 mm), 24 (48%) were seen on only DBT. Microhistological result of architec[...]

Conclusion: In our experience, DBT-VAB allowed to take great advantage of using DBT in breast cancer screening in terms of higher breast cancer detection rate, limiting the potential drawbacks. Indeed, in our series, patients with architectural distortions and a B5 microhistological result have been treated wit[...]

Personal information: 1UOSD Breast Unit ULSS9, Ospedale di Marzana, Piazzale Lambranzi, 1, 37034 Verona/IT   2UOC Anatomia ed Istologia patologica, Ospedale Frà Castoro, Via Circonvallazione, 1, 37047 San Bonifacio (VR)

References: Schrading S, Distelmaier M, Dirrichs T et al (2015) Digital breast tomosynthesis-guided vacuum-assisted breast biopsy: initial experiences and comparison with prone stereotactic vacuum-assisted biopsy. Radiology 274:654-62. Blumen H, Fitch K, Polkus V (2016) Comparison of Treatment Costs for Breas[...]

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