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C-0881 - Lung volumes in fetuses with congenital diaphragmatic hernia: comparison of  US and MR imaging 

H. El Mhabrech1, A. Belaid2, A. Zrig1, O. Kermani3, M. ABDELAALI2, M. Dakkem1, C. Hafsa1; 1 Monastir/TN 2 MONASTIR/TN 3 sousse/TN Type: Scientific Exhibit
Area of Interest: Foetal imaging
Imaging Techniques: MR, Ultrasound
Procedure: Comparative studies
Special Focuses: Hernia, Fetus, Congenital
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Aims and objectives: Congenital diaphragmatic hernia (CDH) occurs with an incidence of approximately 1 in 2200 live births (1). Despite advances in antenatal and postnatal diagnosis and therapy, congenital diaphragmatic hernia is still associated with a high neonatal mortality rate, mainly due to pulmonary hypoplasia an[...]

Methods and materials: A retrospective review of prenatal US and MRI of fetuses with a confirmed diagnosis by surgery or autopsy of CDH. The presence of a chest mass, position of the stomach and liver and visualization of the lungs by US and MRI was noted in all fetuses. The determination of lung area to head circumferenc[...]

Results: The fetuses were 20-40 weeks gestational age (mean 24 weeks). Ultrasound and MRI diagnosed left CDH on 20 cases, right CDH in 3 cases and bilateral CDH in only one case.   Estimate of controlateral lung size and mediastinal shift at level of atria on transverse scan of fetal thorax. With adva[...]

Conclusion: Our results suggest that fetal lung volume in cases with CDH can be estimated either by US or by MRI because both methods had a good agreement. In CDH, the outcome is well known to depend on the occurrence of pulmonary hypoplasia, that is, on the size of the lungs. Prenatal assessment of fetal lung [...]

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References: 1.      Harrison MR, Adzick NS, Estes JM, Howell LJ. A prospective study of the outcome for fetuses with diaphragmatic hernia. JAMA 1994;271: 382 – 384.   2.      Metkus AP, Filly RA, Stringer MD, Harrison MR, Adzick NS. Sonographic predictors of sur[...]

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