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C-0097 - Correlation between port-systemic pressure gradient and changes in platelet count following transjugular intrahepatic portosystemic shunt

A. M. K. Abdel Aal1, S. Kim1, M. Babi1, B. Jackson1, M. Massoud1, S. Moawad1, A. Abouarab1, A. Moustafa2, S. Saddekni1; 1 Birmingham/US 2 Birmingham, AL/US Type: Scientific Exhibit
Area of Interest: Interventional vascular
Imaging Technique: Catheter arteriography
Procedure: Shunts
Special Focus: Outcomes
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Aims and objectives: To demonstrate improvement in platelet count after TIPS To determine if the pre-TIPs platelet count affects the magnitude of change in platelet count after TIPS. To demonstrate if the change in portosystemic pressure gradient (PSG) after TIPS affects the change in platelet count.

Methods and materials: We retrospectively reviewed the medical records of 402 patients who had TIPS placed between January 2005 and December 2015. Patients with platelet count and pressure gradient before and after TIPS were included. A total of 284 patients met the criteria for inclusion. We stratified the patients into [...]

Results: The study included 177 males (62%), 251 Caucasian (88%), with a mean age of 56.6 years. There was a statistically significant increase in overall mean platelet count after TIPS (mean=13.45x103 microL, p<0.0001). There was a statistically significant decrease in overall mean PSG after TIPS (mean= [...]

Conclusion: TIPS results in a significant increase in platelet count which improves the patients' coagulation status. The current study shows statistically significant overall increase in platelet count and statistically significant overall decrease in PSG after TIPS placement. The magnitude of increase in the [...]

Personal information: Ahmed Kamel Abdel Aal, MD, PhD, Chief of Interventional Radiology, Department of Radiology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA. E-mail: akamel@uabmc.edu

References: Liver Transpl. 2012 Mar;18(3):340-6. doi: 10.1002/lt.22456. Hepat Med. 2016 Apr 15;8:39-50. doi: 10.2147/HMER.S74612. eCollection 2016.

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