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C-2163 - Organising pneumonia: atypical imaging findings in a mixed cohort of patients, including those with an underlying malignancy

N. K. Patel1, M. Taylor2, P. Shaw1, E. Borg1, M. Falzon1, A. Ahmed1; 1 London/UK 2 london/UK Type: Educational Exhibit
Area of Interests: Thorax, Respiratory system, Lung
Imaging Techniques: CT, CT-High Resolution, PET-CT
Procedure: Diagnostic procedure
Special Focuses: Cancer, Inflammation
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Learning objectives: To illustrate the atypical presentations of organising pneumonia encountered in patients with and without concomitant malignancy.

Background: INTRODUCTION Organising pneumonia (OP) is classified as one of the idiopathic interstitial pneumonias by the American Thoracic Society and European Respiratory Society (ATS/ERS). It has a distinct histopathological pattern representing a non-specific reparative response to lung injury.   Whil[...]

Findings and procedure details: The following cases feature atypical presentations of confirmed OP in patients with concomitant malignancy undergoing treatment as well as idiopathic cases. This serves to highlight the variable spectrum of appearances on imaging and the difficulty in diagnosis without definitive tissue sampling. [...]

Conclusion: Organising pneumonia in the setting of concomitant malignancy can present a diagnostic challenge particularly in its atypical form where it can morphologically mimic the underlying primary. Patients may present with dense mass like consolidation, spiculated masses or multifocal opacities that do not[...]

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References: 1) Cordier JF. Cryptogenic organising pneumonia. Eur Respir J 2006; 28(2): 422.   2)  Epler GR. Bronchiolitis obliterans organizing pneumonia. Arch Intern Med 2001; 16(12): 158 – 164   3)   Travis WD, Costabel U, Hansell D, et al. An Official American Thoracic Society/Europ[...]

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