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C-2897 - A novel parameter to evaluate thyroid function with dual-energy CT in patients with hyperthyroidism

T. Nakajima, H. Ohtake, D. Binh, T. Higuchi, Y. Tsushima; Maebashi/JP Type: Scientific Exhibit
Area of Interests: Head and neck, Thyroid / Parathyroids
Imaging Techniques: Nuclear medicine conventional, CT
Procedure: Technical aspects
Special Focus: Endocrine disorders
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Aims and objectives: Hyperthyroidism, known as Graves' disease, causes hypermetabolism in most organs resulting in various symptoms, such as palpitation, tachycardia, fatigue, weight loss, and atrial fibrillation. The function of thyroid gland is regulated by thyroid stimulating hormone (TSH). However, TSH receptor anti[...]

Methods and materials: Patients This retrospective study was approved by the institutional review board. Consecutive 13 patients (13 females; mean age, 53.7 ± 13.2 years old) scheduled for radioactive iodine (131I) ablation therapy underwent both the iodine scintigraphy to evaluate thyroid function and the DECT to measure[...]

Results: Moderate positive correlation between the CT values and the calculated iodine concentrations in right and left lobes of the thyroid gland was seen (R = 0.43, p < 0.05) (Fig. 3). The range of the CT values was from 34.5 to 98.7 H.U. (mean ± SD: 67.8 ± 18.6 H.U.) while the iodine concentrations cal[...]

Conclusion: DISCUSSION The comparison between 123I uptakes at 3h and iodine concentration calculated by DECT represented strong negative correlation (Fig. 3b). On the other hand, no correlation between 123I uptakes at 24h and CT values was noted (Fig. 3c). Since the percentile of all of 123I uptakes at 24h were[...]

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References: 1. Baskin, H. J. et al. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Evaluation and Treatment of American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice. Endocr. Pract. 8, 457–469 2. Ron, E. et al. Cancer Mortal[...]

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