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C-2614 - Diffuse-type gastric cancer: specific enhancement pattern on multiphasic contrast-enhanced computed tomography

D. Tsurumaru, M. Miyasaka, T. Muraki, Y. Asayama, H. Honda; Fukuoka/JP Type: Scientific Exhibit
Area of Interests: Stomach (incl. Esophagus), Contrast agents, Gastrointestinal tract
Imaging Techniques: CT-High Resolution, CT
Procedures: Contrast agent-intravenous, Endoscopy, Computer Applications-Detection, diagnosis
Special Focuses: Cancer, Hemodynamics / Flow dynamics
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Aims and objectives: Diffuse-type gastric cancer (DGC), also known as “scirrhous carcinoma” or “linitis plastica,” is a special type of gastric cancer characterized by diffusely infiltrating lesions forming abundant fibrous stroma, and poor distensibility of the stomach depending on the extent of the lesion. Since DGC [...]

Methods and materials: Patient population From September 2006 to December 2015, 21 consecutive patients with DGC who were evaluated by CECTG before treatment were enrolled in our study. The definition of DGC was made based on medical records of endoscopy or fluoroscopy, the findings of which were as follows: an infiltrati[...]

Results: In the MPR image analysis, the median long-axis tumor length was 99.5 mm and the median maximum thickness was 13.8 mm. The number of involved regions were more than tow regions in 15 cases and one in six cases. The maximum circumference involvement was full in 16 cases and non-full in the other five[...]

Conclusion: Our findings suggest that DGCs tend to demonstrate homogeneous wall thickening, and that DGCs tend to be double-layered with a moderately enhanced inner layer and a mildly enhanced outer layer in the arterial phase, and to show a moderately enhanced single-layer in the delayed phase. These specific [...]

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References: 1. Schauer M, Peiper M, Theisen J, Knoefel W. Prognostic factors in patients with diffuse type gastric cancer (linitis plastica) after operative treatment. Eur J Med Res. 2011;16(1):29-33. 2. Salvon-Harman JC, Cady B, Nikulasson S, Khettry U, Stone MD, Lavin P. Shifting proportions of gastric adenoc[...]

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