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C-3069 - Evaluation of metastasis in patients with thymoma: Multimodal imaging with histologic correlation

A. H. Rajaram; Bangalore/IN Type: Scientific Exhibit
Area of Interests: Oncology, Mediastinum
Imaging Techniques: PET-CT, MR, CT
Procedure: Radiation therapy / Oncology
Special Focus: Metastases
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Aims and objectives: Thymomas accounts for ~40% of all mediastinal tumors [1-3]. They have been associated with different paraneoplastic syndromes such as myasthenia gravis, polymyositis, lupus erythematosis, rheumatoid arthritis, and pure red cell aplasia. Thymomas are typically very slow growing tumors that predominan[...]

Methods and materials: Patient population The study population included 200 patients with a histopathological diagnosis of thymomas and thymic carcinomas between 2000 and 2014, who were followed with follow-up cross-sectional imaging study after surgery. At least one post-surgical follow-up scan and a minimum follow-up [...]

Results: Frequency of metastasis and recurrence A total of 1085 scans for the cohort of eligible patients was reviewed. The median time from surgery to the last follow-up scan was 57 months. Among the 200 patients, 67 (33%) demonstrated metastasis or recurrence of thymomas or thymic carcinomas. Patients wi[...]

Conclusion: The present study demonstrated that 33% of patients with thymomas or thymic carcinomas had metastasis or recurrence, and a half of these patients developed three or more episodes of metastasis or recurrence during their disease course. Metastasis or recurrence was more frequently noted in thymic car[...]

Personal information: Akash Rajaram MD, Department of Radiology, M S Ramaiah Medical College, Bangalore, India; akashrajaram@gmail.com

References: 1. Nishino M, Ashiku SK, Kocher ON, et al. The thymus: a comprehensive review. RadioGraphics 2006;26:335-48.   2. Marom EM. Advances in thymoma imaging. J Thorac Imaging 2013;28:69-80.   3. Marom EM. Imaging thymoma. J Thorac Oncol 2010;5:S296-303.   4. Masaoka A, Monden Y, Nakahara K[...]

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