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C-2866 - PI-RADS v2 for predicting prostate cancer Gleason score at final pathology after radical prostatectomy

E. Demozzi, G. Foti, L. Romano, F. Cavicchioli, A. Molinari, S. Cavalleri, G. Carbognin; Negrar/IT Type: Scientific Exhibit
Area of Interests: Genital / Reproductive system male, Oncology, Pelvis
Imaging Techniques: MR-Diffusion/Perfusion, MR
Procedure: Imaging sequences
Special Focus: Cancer
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Aims and objectives: Prostate cancer (PCa) is the second most common cancer in men worldwide [1,2]; it is a heterogeneous disease that ranges clinically from indolent to highly aggressive. The prevalence of prostate cancer increases with age; 34% of men in the 5th decade of life and up to 70% aged 80 years or older have[...]

Methods and materials: Patients This retrospective single-institution study was approved by our institutional review board (IRB) and informed consent was waived for all patients enrolled. The images of 135 consecutive men who underwent mp-MRI examinations at our institution between May 2015 and May 2016 were considered fo[...]

Results: Ninety-four patients with a median age of 63 years (range, 45-73 years) and a median PSA of 9.1 ng/ml (range, 4.5-50 ng/ml) were retrospectively studied after mpRM and radical prostatectomy. The median diameter of the lesions was 11 mm. The median Gleason score was 7 (range, 6–9). Gleason score 6 tu[...]

Conclusion: PI-RADS v2 values were significantly higher in intermediate-high grade prostate cancer; a significant correlation between PI-RADS v2 values and GS in prostatic tumors was determined. This finding may be useful in the non-invasive assessment of the aggressiveness of prostate cancer, which is an impor[...]

Personal information: E.Demozzi, MD, Department of Radiology, “Sacro Cuore Don Calabria” Hospital, Negrar, Via Don Angelo Sempreboni 5, Verona (Italy); emanuele.demozzi@sacrocuore.it G.Foti, MD, Department of Radiology, “Sacro Cuore Don Calabria” Hospital, Negrar, Via Don Angelo Sempreboni 5, Verona (Italy); giovanni.f[...]

References: 1. World Cancer Research Fund International/American Institute for Cancer Research Continous Update Project: Diet, Nutrition, Physical Activity, and Prostate Cancer. 2014. www.wcrf.org/site/default/files/Prostate-Cancer-2014-Report.pdf. Accessed 1 Dec 2015   2. Jemal. American Cancer [...]

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