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B-0232 - Three dimensional structures of alveoli and alveolar ducts on magnified 3D print model based on micro CT of the lung specimen

H. Natori1, H. Takabatake1, M. Mori1, H. Homma1, M. Oda2, K. Mori2, H. Koba1, H. Takahashi1; 1 Sapporo/JP 2 Nagoya/JP Type: Scientific Paper
Area of Interests: Respiratory system, Computer applications, Lung
Imaging Techniques: CAD, CT-High Resolution, Image manipulation / Reconstruction
Procedures: CAD, Computer Applications-3D, Computer Applications-Virtual imaging
Special Focuses: Pathology, Chronic obstructive airways disease
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Purpose: Virtual microscopic images of the peripheral lung specimen by micro CT disclosed structures of the alveolar duct and alveolus. However, fine 3D structures of the alveoli and alveolar ducts have not been reported. Author reported those structures in fine visible form at a glance by magnified 3D print[...]

Methods and materials: Inflated fixed lung specimen was prepared by the method of Heitzman. Size of 5 mm cubic sample was used. FOV of micro CT was 5 or 10 mm in diameter. Data were processed by the original application named as micro-NewVES and NewVES system for 3D vision and virtual endoscopy, created by co-author KM. M[...]

Results:   Virtual micro endoscopic observation disclosed the orifice of the respiratory bronchiole, and then the alveolar duct was appeared. Magnified 3D print model and its virtual images disclosed structures of the alveolar ducts. Naked eye view of a part of the 3D model was shown in Figure 4. A[...]

Conclusion: Magnified 3D model and virtual endoscopic image of the model give us easy to understand knowledges about peripheral lung structures at a glance. This method is useful to establish basics for image analysis of COPD, multi cystic lung diseases, interstitial pulmonary diseases and for many disease[...]

Personal information: Corresponding author: Hiroshi Natori, MD, PhD, emeritus Professor, Sapporo Medical University School of Medicine, Honorary Director of Nishioka Hospital, Sapporo, Japan. hnatori@sapmed.ac.jp

References: 1. Heitzman ER: The Lung, radiologic-pathologic correlations, Markarian B, Dailey ET:  Chapter 2. Mosby, St. Louis, 2nd ed., 1984; p4-12.   2. Mori K, Urano A, Hasegawa J, Toriwaki J, Anno H, Katada K: Virtualized endoscope system - an application of virtual reality technology to diagnosti[...]

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