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C-2488 - Thoracic manifestations of sickle cell disease 

M. Attia1, l. khelil2, H. Neji3, S. HANTOUS1, I. Baccouche1, K. Ben Miled4; 1 ARIANA/TN 2 Tunis/TN 3 Ariana/TN 4 les berges du lac/TN Type: Educational Exhibit
Area of Interests: Lung, Pulmonary vessels, Lymph nodes
Imaging Techniques: CT-Angiography, CT, MR
Procedures: Thrombolysis, Segmentation, Embolisation
Special Focuses: Congenital, Edema, Hypertension
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Learning objectives: The specific aim of this work was to describe the frequent and infrequent thoracic imaging findings in patients with sickle disease anemia. 

Background: •Sickle cell disease is the most frequent hemoglobinopathy .   •It’s an autosomal recessive disease results from the presence of abnormal  globin chains within hemoglobin and may be manifested in anemia, vasoocclusion, and superimposed infection.•it is seen in people from the Middle East [...]

Findings and procedure details: Methods and material 1/Patient selection •we conducted a retrospective study of 22 patients, from January 2007 to september 2016 including all patients, followed in Abderrahmen Mami’s hospital, with background of  sickle cells disease who underwent at least one imaging exam (thorax radiograph[...]

Conclusion: •We have presented a review of thoracic manifestations of sickle cell anemia. • It is important to be aware of the range of radiologic appearances in order to accurately diagnose complications and expedite appropriate treatment.

Personal information:

References: (1)Sickle Cell Anemia: Imaging Findings of Thoracic Complications. Ramírez S., Previgliano C., Sangster G., Simoncini A.(2)ELLIOTT P. VICHINSKY,MD :CAUSES AND OUTCOMES OF THE ACUTE CHEST SYNDROME IN SICKLE CELL DISEASE:New England Journal of Medicine.(3)Practical Management of Haemoglobinopathies:ch[...]

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