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C-2696 - Carbon dioxide gas digital subtraction angiography under temporary microballoon occlusion prior to transcatheter arterial chemoembolisation for hepatocellular carcinoma

J. Koizumi, T. Hara, T. Sekiguchi, S. Ono, T. Ichikawa, T. Kagawa; Isehara/JP Type: Scientific Exhibit
Area of Interests: Interventional vascular, Vascular, Liver
Imaging Technique: Catheter arteriography
Procedures: Chemoembolisation, Balloon occlusion
Special Focuses: Cavitation, Hemodynamics / Flow dynamics
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Aims and objectives: Carbon dioxide (CO2) digital subtraction angiography has been used successfully and safely in many vessels other than cerebral and coronary arteries since 1971 [1]. As compared to liquid iodinated contrast agents, carbon dioxide gas has several advantages: 1) no hypersensitivity reactions, 2) limite[...]

Methods and materials: Informed consent was obtained for this IRB-approved research study, including collection of the clinical data and reporting of the study results.  From June to December 2015, 24 consecutive patients ( Table 1 ; 23 males and 1 female, 73.1±8.9  years) with hepatocellular carcinoma (HCC) whi[...]

Results:     In 24 patients, 31 intrahepatic arteriography ( Table 2 ) was compared. The tumor stain was significantly (p<0.05) better visualized on conventional iodinated contrast under BO (1.8±0.98) than without BO (1.3±1.09). The gas retention was observed in 23 (74.2%) CO2-DSA and detected s[...]

Conclusion: The intraarterial injection of CO2 has contributed to the detection of small HCCs when used in combination with sonography. According to the previous study [4] using a 3Fr. microcatheter showed 100% of APS were shown in 12 patients with known hepatic diseases. Although their study population (includ[...]

Personal information: Correspondence to Jun KOIZUMI, M.D., Ph.D. Associate Professor Department of Diagnostic Radiology School of Medicine, Tokai University 143 Shimokasuya, Isehara city, Kanagawa prefecture 259-1193 JAPAN tel; +81-463-93-1121, fax; +81-463-93-6827 jkoizumi@is.icc.u-tokai.ac.jp

References:     1)         Hawkins IF. Carbon dioxide digital subtraction arteriography. Am J Radiol 1982; 139: 19-24.   2)         Imari Y, Sakamoto S, Shiomochi S, et al. Hepatocellular carcinoma not detected with p[...]

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