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C-2641 - Radiation doses using digital breast tomosynthesis versus digital mammography in a population-based screening program

H. Aase1, C. W. Frøland1, Å. S. Holen2, T. NERAAS1, K. Obst-Gleditsch1, C. K. Sandvik1, K. T. Søvik1, I. M. O. Ulvik1, S. Hofvind2; 1 Bergen/NO 2 Oslo/NO Type: Scientific Exhibit
Area of Interests: Radioprotection / Radiation dose, Breast
Imaging Techniques: Digital radiography, Mammography
Procedure: Screening
Special Focuses: Dosimetric comparison, Epidemiology
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Aims and objectives: Digital breast tomosynthesis (DBT) in combination with digital mammography (DM) in breast cancer screening is shown to increase the detection of breast cancer compared to DM alone [1-8]. However, this technique leads to a doubling of radiation exposure to screened women [1, 9-11]. Software creating [...]

Methods and materials: TOBE is an ongoing randomized controlled trial performed as a part of the Norwegian Breast Cancer Screening Program. Women attending mammography screening in Bergen between January 2016 and December 2017, consenting to participate in the trial will be randomized to be screened with either SM+DBT or [...]

Results: For the 3,120 women screened with DM the cumulative MGD was 4,675.9 mGy, while for the 2,412 women screened with DBT the cumulative MGD was 3,662.4 mGy (Table 1). This resulted in a mean MGD of 1.52 mGy (SD: 0.30, 95% CI: 1.51-1.53) per examination for women screened with SM+DBT. This was statistica[...]

Conclusion: The results imply that screening with SM+DBT results in a statistically higher radiation dose than screening with DM alone. However, while statistically significant, the observed difference in mean MGD might not be of clinical relevance (0.02 mGy). Screening with either SM+DBT or DM alone results in[...]

Personal information: Hildegunn S Aase, MD Breast Centre, Haukeland University Hospital, Bergen, Norway Cecilie W Frøland, MD Breast Centre, Haukeland University Hospital, Bergen, Norway   Åsne S Holen, MSc Cancer Registry of Norway, Oslo, Norway asne.holen@kreftregisteret.no   Tone K Neraas, MD Breast Centre[...]

References: 1. Skaane P, Bandos AI, Gullien R, Eben EB, Ekseth U, Haakenaasen U, et al. Comparison of digital mammography alone and digital mammography plus tomosynthesis in a population-based screening program. Radiology. 2013;267(1):47-56. 2. Ciatto S, Houssami N, Bernardi D, Caumo F, Pellegrini M, Brunelli[...]

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