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C-1268 - GIST: diagnosis and follow-up radiological pearls

J. Delgado Moraleda, R. Piqueras Olmeda, M. Alvarez Martinez, N. Albertz Arévalo, L. LONDOÑO VILLA, A. PICADO BERMÚDEZ; Valencia/ES Type: Educational Exhibit
Area of Interests: Gastrointestinal tract, Management, Abdomen
Imaging Techniques: MR, CT, CT-High Resolution
Procedures: Localisation, Endoscopy, Contrast agent-intravenous
Special Focuses: Cancer, Neoplasia, Metastases
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Learning objectives: Describe the radiologic features of gastrointestinal stromal tumors. Analyze the changes that occur in the tumor due to treatment with tyrosine kinase inhibitors that are useful to characterize the response to treatment. Illustrate these radiological findings with clinical cases of our institutio[...]

Background: Gastrointestinal stromal tumors are the most common mesenchymal tumors of the gastrointestinal tract. Furthermore, they have peculiar radiological characteristics for both diagnosis and monitoring during treatment.

Findings and procedure details: INTRODUCTION Gastrointestinal stromal tumors are the most common type of mesenchymal tumor of gastrointestinal tract origin. Although tumors show similar to smooth muscle cells and histological features of neural origin, they have different characteristics.   The most important of these is th[...]

Conclusion: GIST are relatively common tumors that exhibit specific radiological characteristics for both diagnosis and treatment monitoring. It is important that the radiologist knows these features since they are crucial for patient management.

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References: 1. Hong X, Choi H, Loyer EM, Benjamin RS, Trent JC, Charnsangavej C. Gastrointestinal Stromal Tumor: Role of CT in Diagnosis and in Response Evaluation and Surveillance after Treatment with Imatinib. RadioGraphics. 2006 Mar 1;26(2):481–95. 2. Chourmouzi D, Sinakos E, Papalavrentios L, Akriviadis E[...]

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