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C-3142 - The impact of visceral and subcutaneous fat tissue to the values of T score in postmenopausal women, comparison of DXA and QCT

L. Milisic, B. Hadzihasanovic, S. Hasanovic, J. Arslanagic-Zuban, E. Milisic, D. Bulja; Sarajevo/BA Type: Scientific Exhibit
Area of Interests: Musculoskeletal spine, Musculoskeletal bone
Imaging Techniques: Ultrasound, CT-Quantitative
Procedure: Screening
Special Focus: Osteoporosis
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Aims and objectives: Dual-energy absorptiometry (DXA) measures bone mineral density in grams per square millimeters in a specific area, wherein the thickness of the object does not participate in the calculation. Quantitative computed tomography (QCT) is a method that provides three-dimensional measurement of bone miner[...]

Methods and materials: The study was designed as an observational, cross-sectional, controlled study. The study included 60 patients with value of T score ≤ - 1.0 as determined by DXA (Hologic QDR 4000). The thickness of subcutaneous and visceral fat was measured with ultrasound and bone mineral density was measured with [...]

Results: Table 1. Bone mineral densitometry measured by DXA at the level of lumbar spine     BMC BMD T-score Z-score Total LS 52,3±1,6 0,86±0,02 -2,2±0,2 -0,58±0,2 L1 9,6±0,4 0,75±0,02 -2,1±0,2 -0,7±1,2 L2 11,7±0,4 0,82±0,02 -2,4±0,2 -0,8±0,2 L3 [...]

Conclusion: The average T-score at the level of lumbar spine obtained by DXA in comparison to QCT was not statistically significantly different in patients with osteoporosis who do not have central type of obesity defined as a diameter of visceral fat thickness <41.5 mm. In patients with osteoporosis with ce[...]

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References: 1.Griffith JF, Engelke K, Genant HK. Looking beyond bone mineral density Imaging assessment of bone quality. Ann. N.Y. Acad. Sci. 2010; 1192, 45–56. 2. Yu W, Glueer CC, Fuerst T, Grampp S, Li J, Lu Y, Genant HK. Influence of degenerative joint disease on spinal bone mineral measurements in postmeno[...]

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