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B-0998 - Arterial spin labelling performance in rhombencephalitis diagnosis in children: a study over the last year at Necker Hospital in Paris

I. Cosmina Dana; Paris/FR Type: Scientific Paper
Area of Interests: Pediatric, CNS, Neuroradiology brain
Imaging Techniques: MR-Diffusion/Perfusion, MR
Procedure: Imaging sequences
Special Focus: Infection
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Purpose: The aim of our study was to highlight the arterial spin labelling performance in imaging features of rhombencephalitis of the brain and spinal cord.   Rhombencephalitis is a form of brain stem and cerebellar inflammation that may be life-threatening. It is often difficult to diagnose on the bas[...]

Methods and materials: Retrospective and observational study reviewing records of patients hospitalized in neurology department at Necker Hospital between November 2015 and September 2016. MRI was performed with a 1.5-T and a 3-T units on 76 patients with suspected rhombencephalitis within maximum 4 hours after the onset[...]

Results: Arterial spin labeling (ASL) perfusion MRI imaging was conceived over 20 years ago    The perfusion sequence has several benefits over traditional contrast bolus techniques. First, ASL requires no Gadolinium-based contrast agent. Due to fear of nephrogenic systemic fibrosis, the acquisitio[...]

Conclusion: Arterial spin labelling is a non-invasive technique that provides absolute cerebral blood flow information within a brief period. It has been increasingly used in our department especially in diagnosis of SNC infections . Our results demonstrate the accuracy of ASL in imagining diagnosis of rhombenc[...]

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References: 1.Riikonen R. Infantile spasms: infectious disorders. Neuropediatrics 1993;24:274 –282 2.Alper G, Knepper L, Kanal E. MR findings in listerial rhomben- cephalitis. AJNR Am J Neuroradiol 1996;17:593–596 3.Lorber B. Listeria monocytogenes. In: Long S. Principles and Practice of Pediatric Infectious Di[...]

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