MC 528 - The ABCs of hybrid imaging
MC 528 - The ABCs of hybrid imagingThursday, March 2, 08:30 - 10:00 Room: M 5 Session Type: Joint Course of ESR and RSNA (Radiological Society of North America): Hybrid Imaging Topics: Nuclear Medicine, Imaging Methods, Hybrid imaging Moderators: A. Drzezga (Cologne/DE), K. Riklund (Umea/SE) Add session to my schedule In your schedule (remove)
1. To understand the basics of physics in PET imaging.
2. To learn about the different approaches of PET attenuation correction.
3. To learn about potential artefacts in hybrid imaging.
This lecture covers PET physics without equations, to give a basic understanding of how radioactive decay of anti-matter, positrons, lead to acquisition of positional information of radioactively labelled molecules. In a further step, quantitative tomographic image reconstruction is described. In this step, attenuation correction and the benefits and problems arising from CT-based attenuation correction is described.
1. To learn about MR for attenuation and motion correction.
2. To learn about MR artefacts influencing PET-quality.
3. To understand the complexity of physics in MR/PET.
The introduction of combined PET/MR scanners allows the PET emission data to be corrected for photon attenuation effects using the anatomical MR images. This approach has both advantages and limitations. On the one hand, MR eliminates the radiation exposure associated with CT scans. On the other hand, assumptions regarding the composition of the body based on the available morphological information have to be made since the MR signal does not reflect electron densities. MR physics influences PET in several ways, potentially leading to artefacts and bias that could affect qualitative and quantitative PET studies. The purpose of this presentation is to present such artefacts, describe their origin and impact on PET attenuation correction and discuss strategies to overcome them. Artefacts related to bone and lung tissue misclassification, B0 field inhomogeneity, aliasing/wrap-around, positron-range effects, metallic implants, MR contrast agents, MR hardware, image quality phantoms and subject motion will be discussed.