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C-1903 - Variability of imaging presentation of Typical Pulmonary Carcinoid Tumors. Correlation with pathologic findings.

L. Del Carpio Bellido, A. Agustí, E. Ripoll, F. Zuccarino, M. Cufi, L. Pijuan, A. Gayete, F. Fernandez; Barcelona/ES Type: Educational Exhibit
Area of Interest: Lung
Imaging Techniques: Conventional radiography, CT, PET
Procedure: Diagnostic procedure
Special Focus: Neoplasia
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Learning objectives: To exhibit the variability of presentation of Typical Pulmonary Carcinoid tumors including parenchymal compromise and temporal behavior with conventional x-ray, CT and PET-CT. Describe imaging findings of typical and atypical carcinoids, high grade neuroendocrine tumors, and low aggressive forms o[...]

Background: Pulmonary neuroendocrine neoplasms (NETs) are epithelial tumors from the bronchial Kulchitsky cells, that encompas the whole spectrum of tumors characterized by neuroendocrine morphology and differentiation. A recent 2015 update of the WHO classification of lung tumors provided diagnostic criteria[...]

Findings and procedure details: IMAGING FINDINGS Well-differentiated NETs (CT and AC) share the same radiological characteristics; however, AC may be found more frequently in the periphery in comparison to CT cases (Figure 4).   Plain Radiography   In conventional radiography the most frequent manifestation is a hilar [...]

Conclusion: Pulmonary neuroendocrine neoplasms (NETs) are epithelial tumors from the bronchial Kulchitsky. Lung NETs can be classified into four subtypes:  well-differentiated, low-grade typical carcinoids (TC), well-differentiated, intermediate-grade atypical carcinoids (AC), poorly differentiated, high[...]

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References: M.E. Caplin. Et al. Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoidsl. Annals of Oncology (2015) 26: 1604–1620.   Beasley B. Et al. The 2015 world health organ[...]

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