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B-0923 - Differentiating between benign and malignant axillary lymph nodes in breast cancer patients using sono-elastography and diffusion-weighted MRI

Y. Abdo, M. Abdel Latif, M. Shady; Mansoura/EG Type: Scientific Paper
Area of Interests: Breast, Oncology, Lymph nodes
Imaging Techniques: Ultrasound, MR-Diffusion/Perfusion, Elastography
Procedure: Diagnostic procedure
Special Focus: Cancer
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Purpose: Lymphatic metastasis is the most important prognostic factor in patients with breast cancer. Determination of nodal status is also critical for appropriate treatment planning. Lymph nodes can be detected and visualized by several imaging modalities including ultrasound (US), computed tomography (CT)[...]

Methods and materials: This prospective study was performed during the period from July 2014 to July 2015 at Radiology Department, Mansoura University. It included 30 patients. Their age ranged from 26 to 57 years. Inclusion criteria were the presence of axillary lymph nodes with suspicious criteria or associated with sus[...]

Results: Thirty patients with 30 Lymph nodes were evaluated of which 18 nodes were malignant and 12 nodes were benign.   B-mode ultrasound criteria: There was a statistically significant difference in 3 criteria between benign and malignant nodes; transverse diameter (P =0.0004), cortical thickness[...]

Conclusion: Sonoelastography and DWI can significantly aid in improving characterization and differentiation between benign and malignant axillary nodes, thus reducing the unnecessary invasive biopsies and healthcare costs. The sensitivity, specificity and accuracy of DWI (100%, 91.67% and 96.4%) and sonoelas[...]

Personal information: Yara Abdo, MSc Department of Radiodiagnosis, Mansoura University Student Hospital yaramohamedabdo@gmail.com Mahmoud Abdel Latif, PhD Lecturer of Radiodiagnosis Department of Radiodiagnosis Mansoura University drlatif72@yahoo.com   Magda Shady, PhD Professor of Radiodiagnosis Department of Rad[...]

References: Zhang F, Zhu L, Huang X, et al. Differentiation of reactive and tumor metastatic lymph nodes with diffusion-weighted and SPIO enhanced MRI. Mol Imaging Biol 2013;15(1):40–7. Fornasa F, Nesoti MV, Bovo C, et al. Diffusion-weighted magnetic resonance imaging in the characterization of axillary lymph n[...]

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