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B-1318 - The optimisation of magnetic resonance imaging pulse sequences in order to better detection of multiple sclerosis plaques

J. Abdolmohammadi; Baharan/IR Type: Scientific Paper
Area of Interests: Neuroradiology brain, CNS
Imaging Technique: MR
Procedures: Imaging sequences, Diagnostic procedure
Special Focuses: Demineralisation-Bone, Inflammation, Cerebrospinal fluid
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Purpose: MS is an inflammatory demyelinating disease of the central nervous system (CNS). It is the most common demyelinating disease after vascular- and age-related demyelination. MS is characterized by multiple “plaques” of demyelination in the white matter of the brain and spinal cord. The primary lesions[...]

Methods and materials: In this cross-sectional study which was performed at Shohada-E Tajrish hospital between October, 2011 until April, 2012, included 20 patients who suspected to MS disease were selected by the method of random sampling and underwent routine brain Pulse sequences (Axial T2w, Axial T1w, Coronal T2w, Sag[...]

Results: This study was performed in about 50 lesions and the results in more than 17 lesions showed that, for the Subcortical and Infratentorial areas. The comparison of observed MS plaques in three different MRI Pulse sequences was done by ANOVA test (p<0.05), and the amount of agreement between two neu[...]

Conclusion: MS is an inflammatory demyelinating disease of the CNS which is characterized by multiple “plaques” of demyelination in the white matter of the brain and spinal cord. Magnetic Resonance Imaging Predictors for Disability in Multiple Sclerosis. In some cases, however, the patient has symptoms in which[...]

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References:  ADDIN EN.REFLIST 1.            Lucchinetti CF, Popescu BFG, Bunyan RF, Moll NM, Roemer SF, Lassmann H, et al. Inflammatory cortical demyelination in early multiple sclerosis. New England Journal of Medicine. 2011;365(23):2188-97.   2.[...]

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