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C-2206 - Axial T2 mapping of the lumbar intervertebral disc at 3.0 Tesla for disc pathology assessment

M. W. Raudner1, D. Stelzeneder1, V. Juras2, C. Kronnerwetter1, R. Windhager1, S. Trattnig2; 1 Vienna/AT 2 Wien/AT Type: Scientific Exhibit
Area of Interest: Musculoskeletal spine
Imaging Technique: MR
Procedure: Segmentation
Special Focus: Outcomes
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Aims and objectives: Since T2 mapping can quantify degenerative changes resulting in discogenic pain, can be compared with histological examination and even show short-term changes in water distribution inside the IVDs (1-4), we wanted to assess, whether there are significant differences in axial vs. sagittal T2 value a[...]

Methods and materials: 24 patients (13 men, 11 women; mean age 43.5 years; range 23.5 – 64.2) were examined in a longitudinal study. All patients were evaluated via morphological MRI and T2 mapping was performed in sagittal and axial (one slice per IVD) plane. Inclusion criteria were reported episodes of low back pain and[...]

Results: Axial T2 values of the NP differed significantly from sagittal measurements (mean difference=11.9ms;p<.001) in a paired t-test. Spearman correlation was significant for axial vs. sagittal values (r=.854;p<.001). Axial T2 assessment showed superior results when conducting a t-test for significa[...]

Conclusion: Our data suggests that axial T2 relaxation time measurement may provide superior assessment of the intervertebral disc, especially the nucleus pulposus. The NP T2 values differed in axial vs. sagittal assessment and were slightly lower in the axial evaluation. The axial segmentation, using a circula[...]

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References: (1) D. Stelzeneder, B.K. Kovacs, S. Goed, G.H. Welsch, C. Hirschfeld, T. Paternostro-Sluga, K.M. Friedrich, T.C. Mamisch, S. Trattnig, Effect of short-term unloading on T2 relaxation time in the lumbar intervertebral disc--in vivo magnetic resonance imaging study at 3.0 tesla, Spine J. 12 (2012) 257[...]

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