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B-0471 - Femoral neck strength prediction in osteoporosis patients: trabecular bone analysis using tomosynthesis images

M. Fujii, T. Aoki, S. Yamaguchi, Y. Hayashida, K. Nakano, Y. Okada, K. Saito, Y. Tanaka, Y. Korogi; Kitakyushu/JP Type: Scientific Paper
Area of Interests: Musculoskeletal bone, Bones
Imaging Techniques: CT, Absorptiometry / Bone densiometry, Digital radiography
Procedures: Computer Applications-Detection, diagnosis, Diagnostic procedure
Special Focus: Osteoporosis
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Purpose: Osteoporosis is characterized by an osseous fragility resulting from the low mass and deteriorated microarchitecture in the bone tissue, and frequently increases with age. Hip fractures due to osteoporosis account for majority of medical expenditure and also lead to destructive impact on life qualit[...]

Methods and materials: Subjects Forty-seven consecutive osteoporosis patients were included in this study, from February 2014 to June 2016. They underwent DXA and TS of the bilateral hip joints and CT covering the vertebral body of Th10 to the hip joints within a week.     Tomosynthesis TS examinations were[...]

Results: Amongst the combinations of the BMD and each index of TS images, the combination of BMD with the TSL at the principal tensile group and the VAR at the principal compressive group showed the highest correlation to the failure load by CT-FEM.   The correlation between the failure load and the BMD[...]

Conclusion: Proximal femur fracture is the most severe complication of osteoporosis and is associated with higher mortality and morbidity than any other fracture [7]. With regard to the correlation to the failure load by CT-FEM, our results demonstrated that the contribution ratio of the combination of the TSL [...]

Personal information: Masami Fujii, M.D. Department of Radiology, University of Occupational and Environmental Health School of Medicine, Japan. fujii-m@med.uoeh-u.ac.jp   Takatoshi Aoki, M.D., Ph.D. Department of Radiology, University of Occupational and Environmental Health School of Medicine, Japan. a-taka@med.uo[...]

References: 1) Gullberg B, Johnell O, Kanis J. World-wide projections for hip fracture.   Osteoporos Int 1997; 7:407–13.   2) Johnell O, Kanis J. A. An estimate of the worldwide prevalence, mortality and disability associated with hip fracture. Osteoporos Int 2004; 15, 897–902.   3) Harvey N[...]

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