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C-0579 - Abdominal CT Perfusion: Radiation Dose Reduction using kV change and AEC

T. Yoshikawa1, Y. Ohno1, Y. Fujisawa2, N. Negi1, T. Sekitani1, S. Seki1, Y. Kishida1, K. Sugimura1; 1 Kobe/JP 2 Otawara-Shi/JP Type: Scientific Exhibit
Area of Interests: Pancreas, Liver, Abdomen
Imaging Techniques: CT-Quantitative, Image manipulation / Reconstruction
Procedures: Computer Applications-3D, Radiation safety, Contrast agent-intravenous
Special Focuses: Hemodynamics / Flow dynamics, Tissue characterisation
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Aims and objectives: BACKGROUND Advantages of abdominal CT perfusion (CTP) are minimally invasive technique high ability for quantification wide distribution of CT scanner low cost Abdominal CTP has been suggested to be useful in detection of hepatic micrometastasis characterization of tumor assessment of liver funct[...]

Methods and materials: Patients 111 patients who were suspected to have hepatic metastasis, underwent whole upper abdominal CTP examination. Written informed consent obtained in all patients. This study was limited to assessment of normal subjects proved by at least 6-months follow-up period, because hemodynamics in patie[...]

Results: There was no significant difference in demographic features (fig.1). FOVs. CTDI and DLP of group A (55.8mGy, 894.5mGycm) were significantly higher than those of B (32.2, 529.9) and C (43.5, 696.8) (p<0.0001) (fig.1). There was no significant difference in mean perfusion values between groups A an[...]

Conclusion: DISCUSSION AEC and higher kV can reduce radiation dose without significant changes in perfusion values. In small or thin targets such as portal vein or gastric wall, input function or perfusion values can change possibly due to image degradation caused by dose reduction and physiological motions. Ad[...]

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References: Kim SH, et al. CTPerfusion of the Liver: Principles and Applications in Oncology. Radiology. 2014. O─čul H, et al. Perfusion CT imaging of the liver: review of clinical applications. Diagn Interv Radiol 2014. Cuenod CA, Baet al. Perfusion and vascular permeability: basic concepts and measurement in D[...]

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