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C-2388 - The imaging spectrum of brown adipose tissue: What can we learn about

A. Goienetxea Murgiondo, J. Elejondo Oddo, L. C. Apraiz, A. Ugarte, K. Biurrun Mancisidor, J. A. Vega, A. Gomez Lopez; Donostia/ES Type: Educational Exhibit
Area of Interests: Nuclear medicine, Musculoskeletal system, Hybrid Imaging
Imaging Techniques: MR, PET-CT, Ultrasound
Procedures: Biopsy, Normal variants, Contrast agent-intravenous
Special Focuses: Neoplasia, Education and training, Tissue characterisation
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Learning objectives:   Fig. 15 To understand the physiologic role of brown adipose tissue (BAT) and the methods to assess its presence.   To know the relation between biochemically active pheochromocytoma and brown fat stimulation.   To recognize the imaging findings of hibernomas.  

Background: Two types of adipose tissue are present in the body: white and brown adipose tissue. White adipocytes store excess energy als lipids while brown adipocytes have metabolic or thermoregulatory functions: it expresses uncoupling protein 1 (UCP1) that mediates non-shivering thermogenesis.   BROWN F[...]

Findings and procedure details:   BROWN FAT TISSUE     INTERPRETATIVE PEARLS and PITFALLS     Pitfalls:   It is well recognized that the radiotracer uptake within brown fat is a false-positive when interpreting FDG-PET images. 18F-FDG is highly accumulated in hypermetabolic BAT because glucose, even i[...]

Conclusion: In light of the important role that BAT plays, it is crucial for radiologists to understand the associated physiology and pathology.

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References: Furlong, M. A., Fanburg–Smith, J. C., & Miettinen, M. (2001). The morphologic spectrum of hibernoma: a clinicopathologic study of 170 cases. The American journal of surgical pathology, 25(6), 809-814. Cypess, A. M., Lehman, S., Williams, G., Tal, I., Rodman, D., Goldfine, A. B., ... & Kolodn[...]

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