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C-2856 - Follow-up for women with previous history of breast cancer: could digital breast tomosynthesis be sufficient?

F. Esposito, C. Casella, G. Mariscotti, M. Durando, M. FASCIANO, P. Fonio, G. Gandini; Torino/IT Type: Scientific Exhibit
Area of Interests: Oncology, Breast
Imaging Technique: Mammography
Procedure: Screening
Special Focus: Cancer
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Aims and objectives: Digital Breast Tomosynthesis (DBT) has been developed to improve detection and characterization of breast lesions. It enables to overcome some of the disadvantages of conventional 2D digital mammography (DM), particularly due to overlapping structures. [1-4] Recent literature studies reported that o[...]

Methods and materials: A retrospective study was performed on a cohort of 203 women with a previous personal history of breast cancer; all patients underwent conventional 2D DM combined with DBT between January 2010 and December 2015 in our Breast Imaging Service, for at least three rounds of their routine mammographic su[...]

Results: The overall performances of DBT combined with conventional 2D DM were respectively sensitivity 92% (figure 1-4), specificity 83% and diagnostic accuracy 84%, negative predictive value 99% and positive predictive value 44% (table 1). In the study population, the rate of indeterminate or suspicious fi[...]

Conclusion: The addition of DBT to conventional 2D DM in the surveillance of the patients with a previous personal history of breast cancer treatment or in oncologic follow-up, leaded to high negative predictive value (99%), even though the rate of indeterminate or suspicious findings generated by DBT prompted [...]

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References: 1.     1. Skaane P, Bandos AI, Gullien R et al. Comparison of digital mammography alone and digital mammography plus tomosynthesis in a population-based screening program. Radiology 2013; 267(1):47-56.   2.      2. Andersson I, Ikeda DM, Zackrisson S et al. B[...]

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