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C-2913 - What to do when Transient Elastography is not feasible?

R. Lupusoru, I. Sporea, A. Popescu, R. Sirli, R. Moleriu, C. Zaharia; Timisoara/RO Type: Scientific Exhibit
Area of Interests: Abdomen, Liver
Imaging Technique: Elastography
Procedure: Decision analysis
Special Focus: Education and training
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Aims and objectives: Liver fibrosis is the common end-point of a variety of chronic liver diseases. The progression of liver fibrosis leads to cirrhosis, decompensation, liver failure, hepatocellular carcinoma (HCC) and death. In current clinical practice, TE is the most widely used elastography technique used for the n[...]

Methods and materials: Liver stiffness values were assessed by four shear-waves elastography techniques: transient elastography (TE - FibroScan® device from EchoSens®); 2D shear wave elastography (SSI - Aixplorer® system from SuperSonic Shear Imaging) and point shear wave elastography (pSWE) using Virtual Touch Quantifica[...]

Results: The correlation between the results of measurements made by TE, VTQ, SSI and ElastPQ were very good: 0.84, 0.85, 0.85 respectively. (Fig. 1, Fig. 2, Fig3.) The model to estimate the severity of fibrosis which included all three elastographic techniques (factors) - ElastPQ+SSI+VTQ as compared with [...]

Conclusion: SSI in combination with ElastPQ or VTQ is as good as the TE used alone. Therefore these combination can be used when TE can’t be made or when valid measurements cannot be obtained.

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References: 1.Tsochatzis EA el al,.Elastography for the diagnosis of severity of fibrosis in chronic liver disease: a meta-analysis of diagnostic accuracy.J Hepatology 2011 Apr; 54(4)650-9. 2.Nierhoff J, et.al . The efficiency of acoustic radiation force imaging for the staging of liver fibrosis: a meta-analysi[...]

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