C-0459 - Cerebellar hemiatrophy: Literature Review with an illustrative case
C-0459 - Cerebellar hemiatrophy: Literature Review with an illustrative caseB. F. B. B. Abreu1, M. Duarte1, A. Silva2, J. Prado3, M. Silva3; 1 Santos/BR 2 Imperatriz/BR 3 São Paulo/BR Type: Educational Exhibit
Area of Interests: Neuroradiology brain, Head and neck, CNS
Imaging Technique: MR
Procedures: Normal variants, eLearning, Education
Special Focuses: Education and training, Epidemiology, Congenital
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Learning objectives: Elucidate a diagnose of cerebellar hemiatrophy that is a nonspecific finding in neuroimaging studies of children with multitude of different findings.
Background: Atrophy, in general terms, implies (irreversible) loss of tissue1,2. Mitochondrial disease was the most common cause of cerebellar atrophy, according to Al-Maawali3. It´s important to notice that vast majority of hereditary cerebellar atrophy does not lead to significant brainstem atrophy, even in a[...]
Findings and procedure details: Neuroimaging like computed tomography (CT) and magnetic resonance imaging (MRI) play key diagnostic role in neurology, especially paediatric2 – the axial section is the best section to see cerebellar atrophy of the hemispheres1. The presence of cerebellar atrophy on neuroimaging can facilitate selec[...]
Conclusion: Although uncommon, cerebellar hemiatrophy should be investigated for additional findings and for the investigation of its possible causes.
References: 1. Poretti A, Wolf NI, Boltshauser E. Differential diagnosis of cerebellar atrophy in childhood. Eur J Paediatr Neurol. 2008 May;12(3):155-67. 2. Uduma FU, Emejulu JK, Motah M, Okere PC, Ongolo PC, Muna W. Differential diagnoses of cerebral hemiatrophy in childhood: a review of litera[...]