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C-2185 - Breast lesions related to pregnancy and lactation - a diagnostic challenge

M. Szep, A. R. Chiorean, M. A. Chiorean, M. Duma; Cluj Napoca/RO Type: Educational Exhibit
Area of Interests: Radioprotection / Radiation dose, Breast
Imaging Techniques: Mammography, MR, Ultrasound
Procedure: Biopsy
Special Focus: Cancer
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Learning objectives: To highlight the selection of the appropriate imaging workup and intervention for evaluating the breast during pregnancy and lactation. Describe radiologic manifestations of the most common disorders. Discuss the most common and relevant clinical and radiologic manifestations of pregnancy-associated[...]

Background: Pregnancy and lactation represent physiologic states that induce changes in the mammary glands in response to hormonal stimulation (estrogen, progesterone and prolactin). These changes begin early in the the 1st trimester of pregnancy and lead to a diffuse and marked increase in parenchymal density [...]

Findings and procedure details: A retrospective study was performed including all those pregnant and lactating women investigated for palpable masses during a 3-year period. Radiographic findings, pathology results, and clinical notes were reviewed. Aspects were assessed according to BI-RADS and Tsukuba elasticity score [9,10]. Im[...]

Conclusion: Knowledge of the entities that are specifically related to pregnancy and lactation and of their imaging appearances are essential for an accurate diagnosis. The standard method for assessing these breast disorders is ultrasound combined, if needed, with core needle biopsy. The possibility of breast [...]

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References: 1. Sabate JM et al. Radiologic evaluation of breast disorders related to pregnancy and lactation. Radiographics. 2007 Oct;27 Suppl 1:S101-24. 2.  Ayyappan A.P. et al. Pregnancy-associated breast cancer: spectrum of imaging appearances. The British Journal of Radiology, 83 (2[...]

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