Local Time : 22:34 CET

B-0691 - Stratification of arrhythmic risk in HCM patients on the basis of oedema and myocardial scar on late gadolinium enhancement-cardiac magnetic resonance (LGE-CMR): a 11-year follow-up study

S. Bertugno, L. Nocetti, F. Fiocchi, A. Barbieri, Y. Bartolacelli, P. Torricelli, G. Ligabue; Modena/IT Type: Scientific Paper
Area of Interests: Contrast agents, Cardiac
Imaging Technique: MR
Procedures: Computer Applications-Detection, diagnosis, Contrast agent-intravenous
Special Focuses: Hyperplasia / Hypertrophy, Edema
Add poster to my schedule In your schedule (remove)

Direct link to access the poster (click here)

Purpose: Hypertrophic Cardiomyopathy (HCM) is a complex and fairly frequent familiar cardiac disease (1:500), characterized by extreme heterogeneity with respect to genetic, phenotypic and clinical expression and pathophysiological substrates [1]. Clinical presentation ranges from asymptomatic or mildly symp[...]

Methods and materials: Study population: One hundred fifty consecutive patients with HCM were enrolled and underwent LGE-CMR examination between September 2005 and August 2016 at University Hospital Policlinico di Modena. HCM diagnosis was based on established clinical criteria: family history, clinical examination, echoc[...]

Results: Study population: All 150 patients were included in the analysis. Demographic and clinical characteristics at baseline are summarized in Table 1. Mean age was 55±16 years (range 18 to 79 years); 109 patients (73%) were male. Forty-nine (33%) patients presented a familiar form of HCM. Of the 150 pati[...]

Conclusion: In HCM patients, even if asymptomatic or mildly symptomatic, the extent of fibrosis and the presence of oedema, identified respectively by LGE and T2 hyperintensity on CMR examination, were independent predictors of VT. Our findings support the hypothesis that macroscopic  fibrosis and oedema [...]

Personal information: Personal e-mail: serena.bertugno@gmail.com

References: 1. Maron BJ. Hypertrophic cardiomyopathy: a systematic review. JAMA 2002;287:1308–20. 2. Varnava AM, Elliott PM, Mahon N, Davies MJ, McKenna WJet al. Relation between myocite disarray and outcome in hypertrophic cardiomyopathy. American Journal of Cardiology 2001;88:275–9. 3. Melacini P, Corbetti F,[...]

This website uses cookies. Learn more