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C-0634 - Assessing treatment response in pancreatic cancer: role of different imaging criteria

E. Boninsegna1, R. Negrelli1, G. A. Zamboni1, G. Avesani2, R. Manfredi1, R. Pozzi-Mucelli1; 1 Verona/IT 2 Bolzano/IT Type: Educational Exhibit
Area of Interests: Pancreas, Oncology, Abdomen
Imaging Techniques: CT, MR-Diffusion/Perfusion, PET-CT
Procedures: Chemotherapy, Diagnostic procedure, Decision analysis
Special Focuses: Neoplasia, Metastases, Tissue characterisation
Please note: This poster is part of the session VoE 83 - Italian on Saturday, March 4, 10:00 - 11:00 Add poster to my schedule In your schedule (remove)

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Learning objectives: The objectives of the current Poster are:   To review the different treatment response criteria in patients with pancreatic ductal adenocarcinoma To suggest the most useful imaging features to assess tumor modifications after chemotherapy To investigate the possible response criteria of the co[...]

Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the leading neoplasms of the gastrointestinal tract and the twelfth most common cancer in the world [1]. Due to the lack of effective screening programs, by 2030 pancreatic cancer is projected to surpass breast, lung, and colorectal cancers to become[...]

Findings and procedure details: RECIST CRITERIA The original Response Evaluation Criteria In Solid Tumors (RECIST version 1.0) were proposed on 2000 jointly by several scientific Organizations, including WHO [8].  They evaluated modifications of longest diameter of the neoplasm, and progressive disease was defined as the[...]

Conclusion: Assessing treatment response of pancreatic ductal adenocarcinoma is complex; dimensions, density and tumor-vessels contact should be evaluated, but often they are not enough. For most cases it is necessary to assess also the diffusion coefficient, metabolic activity of the neoplasm and its heterogen[...]

Personal information:

References: 1. wcrf.org/int/cancer-facts-figures/data-specific-cancers/pancreatic-cancer-statistics 2. Rahib L, Smith BD, Aizenberg R, Rosenzweig AB, Fleshman JM, Matrisian LM. Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States. C[...]

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