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C-2644 - Diffusion kurtosis imaging for differentiating parotid tumours

C. Li, J. YU, Y. Lü, H. Zhang, B. Zhao; Jinan/CN Type: Scientific Exhibit
Area of Interests: Neuroradiology peripheral nerve, Neuroradiology brain, Head and neck
Imaging Techniques: Neural networks, MR-Diffusion/Perfusion, MR-Functional imaging
Procedures: eLearning, Sialography, Imaging sequences
Special Focuses: Neoplasia, Hemorrhage, Cerebrospinal fluid
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Aims and objectives: The purpose of the study is to elucidate the utility of diffusion kurtosis imaging (DKI) for differentiation of parotid tumors.

Methods and materials: 32 patients with 34 parotid tumors were examined with conventional magnetic resonance imaging (MRI) and DKI. The data of DKI were analyzed with Diffusion Kurtosis Estimator to calculate mean kurtosis (MK) mean diffusivity (MD) and fractional anisotropy (FA). The diagnostic accuracy of MK, MD and FA [...]

Results: There was a significant difference of benign and malignant parotid tumors in the values of MK, FA and MD (P=0.003, 0.019 and 0.047). The mean MK value of benign parotid tumors was significantly lower than malignant parotid tumors (0.73±0.27 vs 1.09±0.25, respectively). The mean FA value of benign pa[...]

Conclusion: our results demonstrate significant differences in mean MK between benign and malignant parotid tumors. It is better in discriminating benign and malignant parotid tumors by mean MK than by conventional diffusion weighted and tensor imaging parameters. This new technique potentially can be used as a[...]

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References: 1:   Habermann CR, Arndt C, Graessner J, et al. Diffusion-Weighted Echo-Planar    MR Imaging of Primary Parotid Gland Tumors: Is a Prediction of Different Histologic Subtypes Possible? Am J Neuroradiol. 2009;30(3):591-596               &nbs[...]

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