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C-1177 - Concurrent CAD with Digital Breast Tomosynthesis Improves Reading Time and Maintains Performance for Dedicated Breast Radiologists and General Radiologists

R. A. Benedikt1, A. Toledano2, J. Boatsman1, J. Arfi Rouche3, B. Boyer4, J. Hoffmeister5, C. Balleyguier3; 1 San Antonio/US 2 Washington/US 3 Villejuif/FR 4 Paris/FR 5 Nashua/US Type: Scientific Exhibit
Area of Interests: Computer applications, Breast
Imaging Techniques: Mammography, CAD
Procedures: Efficacy studies, Observer performance, CAD
Special Focus: Cancer
Please note: This poster is part of the session VoE 29 - Breast on Sunday, March 5, 10:00 - 11:00 Add poster to my schedule In your schedule (remove)

Direct link to access the poster (click here)

Aims and objectives: The addition of Digital Breast Tomosynthesis (DBT) to Full-Field Digital Mammography (FFDM) has been shown to improve cancer detection rates by about 30% and lower recall rates by about 15% [1,2], but approximately doubles reading time compared to FFDM alone [1,3,4].   A novel Computer-Aid[...]

Methods and materials: A pivotal reader study was conducted with 20 radiologists retrospectively reading 240 DBT cases, including 67 malignancies in 60 patients. All cases were reviewed with and without CAD, and with a washout period of at least 4 weeks (Figure 1).   Concurrent CAD detects and extracts suspicious mas[...]

Results: For breast radiologists, reading time improved 27.7% with concurrent use of CAD (95% CI: 14.5%, 38.8%; p < 0.01) from an average of 65.8 sec without CAD to 47.7 sec with CAD, and improved 30.5% (95% CI: 17.5%, 41.4%; p < 0.01) for general radiologists (Figure 4) from an average of 65.0 sec wit[...]

Conclusion: The impact of concurrent CAD with DBT on breast radiologists and general radiologists was similar. Average reading time improved about 30% while maintaining sensitivity, specificity, and AUC.

Personal information: Richard Benedikt, Intrinsic Imaging, LLC, San Antonio, TX, US, Richard.Benedikt@intrinsicimaging.com    Alicia Y. Toledano, Biostatistics Consulting, LLC, Kensington, MD, US, alicia.toledano@post.harvard.edu   Justin Boatsman, Intrinsic Imaging, LLC, San Antonio, TX, US, jus[...]

References: 1. Skaane P, Bandos AI, Gullien R, et al. Comparison of digital mammography alone and digital mammography plus tomosynthesis in a population-based screening program. Radiology 2013; 267:47-56. 2. Friedewald SM, Rafferty EA, Rose SL, et al. Breast cancer screening using tomosynthesis in combination w[...]

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