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C-0884 - High intensity focused ultrasound treatment for relapsing extra-abdominal desmoid tumours
A. Najafi, C. A. Binkert; Winterthur/CH
Type: Scientific Exhibit
Area of Interests: Interventional non-vascular, Musculoskeletal soft tissue, Oncology
Imaging Techniques: MR, Ultrasound
Procedures: Ablation procedures, Treatment effects
Special Focus: Multidisciplinary cancer care

Aims and objectives:
Desmoid tumors are locally infiltrative, non-malignant soft tissue tumors. Based on location, desmoids are divided into extra-abdominal (trunk and extremities) and intra-abdominal tumors. Risk factors are prior surgery or trauma and pregnancy. Due to the chronic and highly variable nature of disease[...]
Methods and materials:
Five patients with relapsing, pathologically proven desmoid tumors (three males, two females; age range 40–79 years) were treated with MR-HIFU. Two patients had desmoids located in the rectus abdominis muscle, one in the deltoid muscle, one in the intercostal muscles and one in the popliteal fossa. [...]
Results:
MR-HIFU was technically successful in all patients without severe side effects. In one patient with desmoid in the popliteal fossa, the deeper parts of the tumor could not be targeted because of proximity to nerve and vessel structures. Follow-up periods range from 2 to 60 months. Initial targeted m[...]
Conclusion:
MR-HIFU is an effective, outpatient treatment for patients with desmoid tumors that has minimal side effects and that can be combined with other treatment modalities. Given that desmoids are non-malignant tumors, the main treatment approach should be local tumor control while minimizing side effects[...]
Personal information:
A. Najafi, MD Canton Hospital Winterthur, Institute of Radiology and Nuclear Medicine, Winterthur, Switzerland. Brauerstrasse 15 8401 Winterthur, Switzerland Phone: + 41522664117 E-mail : arash.najafi@ksw.ch
References:
1. Merchant NB, Lewis JJ, Woodruff JM, Leung DH, Brennan MF (1999) Extremity and trunk desmoid tumors: a multifactorial analysis of outcome. Cancer 1999;86(10):2045-52. 2. Gronchi A, Casali PG, Mariani L, Lo Vullo S, Colecchia M, Lozza L, Bertulli R, Fiore M, Olmi P, Santinami M, Rosai J (2003) Qual[...]

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