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C-2567 - Association of spontaneous hyperdense middle cerebral artery sign (HMCAS) with intravenous recanalization rates in patients with acute ischemic stroke (AIS)
R. BRAHIM1, N. Mama2, T. Kamoun2, O. Kermani2, Y. BEN CHEIKH3, A. Ben Abdallah2, H. Jemni2; 1Kairouan/TN 2SOUSSE/TN 3Sousse/TR
Type: Scientific Exhibit
Area of Interest: Vascular
Imaging Technique: CT
Procedure: Thrombolysis
Special Focus: Hemorrhage

Aims and objectives:
The current management of acute ischemic stroke in our local neurological intensive care unit is based on intravenous (IV) recombinant tissue plasminogen activator (rtPA). The presence of a hyperdense middle cerebral artery sign (HMCAS) on non enhanced CT (NECT) is considered to be poor prognostic s[...]
Methods and materials:
We performed a retrospective analysis including 36 consecutive patients admitted between January 2016 and December 2017 to neurological intensive care unit with acute ischemic stroke presenting within 4 hours and treated by intravenous thrombolysis. (alteplase: Infuse 0.9 mg/kg (maximum dose 90 mg) [...]
RESULTS: There were 12 women and 24 men with mean age 66±13(SD) years. HMCAS has been identified in 16 cases (fig 2). Results were compared between HMCAS group and control group (table2). Average ASPECT score and time to treatment were nearly the same in both groups. On 24 hours NECT follow-up, the [...]
On univariate analysis, hyperdense middle cerebral artery sign [HMCAS], showed no significant correlation with early improvement, recanalization rates and haemorrhagic transformation. This study has several limitations: It’s a retrospective study with limited number of HMCAS and control group case[...]
Personal information:
1.Ming Zou a,b, Leonid Churilov c, Anna He b,et al.Hyperdense middle cerebral artery sign is associated with increased risk of hemorrhagic transformation after intravenous thrombolysis for patients with acute ischaemic stroke.Journal of Clinical Neuroscience 2013;33:446–52. 2.Wardlaw JM, Mielke O. E[...]

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